We study genetic forms of heart failure. Using tools at the interface of biochemistry, synthetic biology, and bioengineering, we investigate the molecular pathways underlying disease. Our goal is to develop therapeutic strategies to prevent disease progression.
We are a collaborative team of research scientists spanning a range of educational experiences. We believe diversity in the team is fundamental to interdisciplinary research and scientific advancement. Our lab welcomes contributions from all individuals and value each person’s unique perspective. Innovation in research thrives in an environment where we respect and support each other.
Human induced pluripotent stem cells (iPSCs) provide the molecular context to study disease progression in human cells. To study how genetics affects disease progression, we convert somatic cells to pluripotent stem cells that have the potential to become any cell type. We are grateful to patients who have donated their blood to make these stem cells. By making heart cells from stem cells, we can study the molecular basis of disease with respect to the heart. We compare healthy and diseased states in these cells that have the same genetic make-up as the individual who donated their cells.
Join Our Team
We are looking for enthusiastic and motivated scientists to join our research group. Interested candidates can send their CV to Asuka Eguchi.